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Skin care just got smarter. Next-gen smart serum delivers what your skin needs, when and where it needs it. Delivers a personalized response every time, for healthier-looking skin over time.
SmartResponse technology helps stop skin damage before it starts – using four smart actives which, when triggered, hydrate, brighten, soothe, and address the appearance of fine lines and wrinkles in response to skin’s changing needs. Oligosaccharides from hydrolyzed Beta Glucan respond to dehydration signals, helping skin to maintain optimal hydration levels. Hydrolyzed Wheat Flour, rich in arabinoxylo-oligosaccharides, activates as needed to brighten and help reduce the appearance of dark spots. Antioxidant-rich Japanese Cornelia Cherry helps to protect stressed skin against free radicals, helping to soothe and reduce the appearance of redness. Plant-based Mannose-6-Phosphate visibly smooths and provides a firming effect, responding to the first signs of visible skin aging to help improve the look of fine lines and wrinkles. Lactic Acid, an Alpha Hydroxy Acid (AHA), helps to brighten and smooth skin.
Expiry Date: 01/Jan/2028
Water/Aqua/Eau, Glycerin, Coco-Caprylate/Caprate, PPG-24-Glycereth-24, Niacinamide, Butylene Glycol, 1,2-Hexanediol, Sodium Acrylates Crosspolymer-2, C18-36 Acid Triglyceride, Sodium Polyacryloyldimethyl Taurate, Hydroxyacetophenone, Jojoba Esters, Olive Oil Decyl Esters, Phytosterols, Cornus Officinalis Fruit Extract, Hydrolyzed Wheat Flour, Sodium Mannose Phosphate, Phytosteryl Macadamiate, Hydrolyzed Beta-Glucan, Mimosa Tenuiflora Bark Extract, Ilex Paraguariensis Leaf Extract, Sea Salt, Ferula Galbaniflua (Galbanum) Resin Oil, Helianthus Annuus (Sunflower) Seed Oil, Citrus Aurantium Bergamia (Bergamot) Fruit Extract, Citrus Aurantium Dulcis (Orange) Peel Oil, Juniperus Virginiana Oil, Pelargonium Graveolens Flower Oil, Vetiveria Zizanoides Root Oil, Prunus Amygdalus Amara (Bitter Almond) Kernel Oil, Chlorella Vulgaris Extract, Dipteryx Odorata Seed Extract, Lactic Acid, Bentonite, C12-18 Acid Triglyceride, Squalene, Tocopherol, Sodium Acetylated Hyaluronate, Mannose, Citric Acid, Hydrated Silica, Sodium Benzoate, Potassium Sorbate, Citronellol, Geraniol, Coumarin, Linalool, Limonene.
Dermalogica is dedicated to maintaining the accuracy of the ingredient lists on this website. However, because ingredients are subject to change, we cannot guarantee that these lists are complete, up-to-date and/or error-free. For an accurate listing of ingredients in each product, please refer to your product packaging.
FAQs
What skin types is Smart Response Serum recommended for?
Recommended for all skin types, including dryness/dehydration, fine lines and wrinkles, enlarged pores, sensitivity, and redness.
What does this serum do?
Delivers targeted hydration, brightening, soothing, and helps address the appearance of fine lines and uneven tone using SmartResponse actives.
What are the key active ingredients?
The key ingredients include Oligosaccharides from hydrolyzed Beta Glucan respond to dehydration signals, helping skin to maintain optimal hydration levels. Hydrolyzed Wheat Flour, rich in arabinoxylo-oligosaccharides, activates as needed to brighten and help reduce the appearance of dark spots. Antioxidant-rich Japanese Cornelia Cherry helps to protect stressed skin against free radicals, helping to soothe and reduce the appearance of redness. Plant-based Mannose-6-Phosphate visibly smooths and provides a firming effect, responding to the first signs of visible skin aging to help improve the look of fine lines and wrinkles.
How do I use Smart Response Serum?
Apply to cleansed skin. Use in the morning and/or evening, follow with your moisturizer, and allow it to absorb before applying makeup.
What is the texture like?
Lightweight gel-cream texture that absorbs and layers well; many users report a dewy, hydrated finish.
Does it have a scent?
Dermalogica formulas never use artificial fragrances. However, botanical extracts and essential oils included for skin benefits may have a natural scent. Some users may notice a subtle fragrance.
Can I layer this with other products?
Yes - it layers well under moisturizers and makeup and is commonly used within multi-step routines.
Is Smart Response Serum suitable for sensitive skin?
Formulated to soothe and reduce the appearance of redness for many users. If you have known sensitivities, consider a patch test before full use.
protects, preps, enhances
protects, preps, enhances
nourishes and fades dark spot
nourishes and fades dark spot
hydrates and combats skin ageing
hydrates and combats skin ageing
defends against skin damage
defends against skin damage
boosts skin's natural luminosity
boosts skin's natural luminosity
visibly lifts dark spots
visibly lifts dark spots
exfoliates, brightens and firms
exfoliates, brightens and firms
brightens and boosts radiance
brightens and boosts radiance
brightens dull uneven skin tone
brightens dull uneven skin tone
exfoliates, smooths, brightens
exfoliates, smooths, brightens
deeply hydrates and replenishes
deeply hydrates and replenishes
reduces fine lines and hydrates
reduces fine lines and hydrates
protects, preps, enhances
protects, preps, enhances
melts makeup and impurities
melts makeup and impurities
smooths and nourishes
smooths and nourishes
washes away impurities
washes away impurities
Provides 48 hours of hydration
Provides 48 hours of hydration
preps, hydrates and refreshes
preps, hydrates and refreshes
Moisturizes dry, depleted skin
Moisturizes dry, depleted skin
exfoliates, calms, restores
exfoliates, calms, restores
clears and prevents breakouts
clears and prevents breakouts
firms, depuffs and brightens
firms, depuffs and brightens
provides oil-free hydration
provides oil-free hydration
defends against skin damage
defends against skin damage
nourishes chronically dry skin
nourishes chronically dry skin
Overall rating: 4.8048534 / 5 from 989 reviews.
The Smart Response 4-in-1 Face Serum is praised for its ability to deliver personalized skin care, hydrating, brightening, soothing, and reducing the appearance of fine lines and wrinkles. Customers appreciate its smooth texture, pleasant smell, and noticeable results.
Review topics: ["acne","breakouts","ingredients","fit","irritation","wrinkles","redness","break outs","size","results","fragrance","issues","eyes","pores","smell","effect","absorbs","weight","liquid","reaction","spots","skin","residue","dryness","improvement","hydration","quality","other products","benefits","oil"].
"I’ve used Dermalogica for years, and Smart Response Serum is a standout. It leaves my skin feeling renewed, smooth, and deeply hydrated. I’ve even received compliments while wearing only this serum. It’s become an essential in my routine."
"Have used for 3 days and I love it! Redness has improved and I have sensitive skin but so far so good!!. It’s pricey but I think will last a long time."
"Love this serum and carrying it around when my skin needs a boost of hydration"
"The bottle design is nice and packaging. Quick delivery! I feel hydrated all day but I'm not sure if it brightens or I feel more glowy for the price. I do love all dermalogica products though."
"Firstly I received the sample, and then fell in love with this product!I use it before going to bed, and my skin says thanks to me, it's so glowing and soft!"
"The Smart Response Serum delivered results I could actually see. My skin looked noticeably smoother, brighter, and more even in tone, and the difference between my before-and-after photos was undeniable. The formula absorbs beautifully—lightweight, hydrating, and never sticky—and it leaves my complexion calm, radiant, and refreshed. This has quickly become a standout step in my routine."
"So far I like it! Received a few samples over a period of time and will wait a little longer before purchasing but so far it’s nice!"
"Perfect serum for the cold weather. It is thick and goes on so smoothly. Definitely helps with hydration and works wonderful when applying moisterizer on top of it."
"This is my favorite product by Dermalogica. I feel like it smooths my face like no other produce. I like putting it on over my foundation for a little trick."
"The product is good! It’s been helping a bit to keep my rosacea flare-ups under control. I know it’s not a medication, but it really helps keep my skin moisturized. My only issue is the quantity — for such a high price, it feels too little. Also, the bottle is quite heavy, so it’s hard to tell when you’re running low. Maybe adding a transparent indicator on the side would help? Instead of spending so much on fancy packaging, I’d prefer if the price were lower or the quantity increased."
